In patients undergoing maxillary sinus floor elevation (MSFE) for dental implant placement, bone substitutes are currently evaluated as alternatives for autologous bone.Continue reading
Human mesenchymal stem cell treatment
of premature ovarian failure: new
challenges and opportunities
Premature ovarian failure (POF) is one of the common disorders found in women leading to 1% female infertility.Continue reading
Stem cell enriched lipotransfer reverses the
effects of fibrosis in systemic sclerosis
Oro-facial fibrosis in systemic sclerosis (Scleroderma;SSc) has a major impact on mouth function, facial appearance, and patient quality of life. Lipotransfer is a method of reconstruction that can be used in the treatment of oro-facial fibrosis.Continue reading
Intratendinous adipose-derived stromal vascular fraction (SVF) injection provides a safe, efficacious treatment for Achilles tendinopathy: results of a randomized controlled clinical trial at a 6-month follow-up
Purpose Although platelet-rich plasma (PRP) injection has shown controversial results for the treatment of Achilles tendinopathy, it remains the most used biological treatment. Recent findings seem to demonstrate that the stromal vascular fraction (SVF) within adipose tissue may counteract the impaired tendon homeostasis.Continue reading
Stem Cell Storage: Intermediary companies fail, but there are still Biobanks to rely on like SSCB
“The failure and mismanagement of other Biobanks for Stem Cell Preservation ruin our sector”, speaks Dr. Luca Mariotta, Scientific Director of SSCB.
Last week, Ticinonews reported on a young couple who were looking for their baby’s cells after the company they had contracted with, Genico, disappeared. Cantonal pharmacist Giovan Maria Zanini said he was concerned about Switzerland’s free-market policy in such a sensitive area.
Fat as a source of stem cells for regenerative and aesthetic medicine
Did you know that SSCB offers you the possibility to store stem cells from fat tissue? Fat tissue is a rich source of stem cells that are widely used in regenerative and aesthetic medicine. But how is fat tissue harvested? The fat is easily and safely harvested through mini-liposuction, which is performed by a doctor.
Thanks to this minimally invasive procedure, you can store your fat and avoid major liposuction or the use of synthetic fillers.
Stem Cells from Adipose Tissue
SSCB from this year, thanks also to its GMP (Good Manufacturing Practice) certification, offers a new service to its customers, giving the possibility to store stem cells from adipose tissue for potential future use.Continue reading
Stem cell secretome from adipose tissue as a biotherapeutic agent to inhibit growth of triple-negative breast cancer
n this experimental study, a protocol was developed for processing a formulation derived from secretome obtained from adipose tissue mesenchymal stem cells at different concentrations. Its molecular composition and in vitro efficacy was evaluated when applied to breast cancer cell lines. In addition, the ability of the formulation to suppress the growth of triple-negative breast cancer when infused into a mouse model of the disease was verified.Continue reading
Intracerebral infusion of adipose tissue stem cells to treat chronic ischaemic stroke
Current therapies do not induce significant benefits in chronic stroke patients. Preclinical studies suggest that autologous transplantation of adipose tissue stem cells may be of benefit. This phase one clinical trial was developed to test the safety and efficacy of adipose tissue mesenchymal stem transplantation in chronic stroke patients.Continue reading
Outcomes of adipose tissue stem cell transplantation for the treatment of refractory lupus nephritis
To date, the immunomodulatory capacity of mesenchymal stem cells is well known. In this phase one clinical trial, the efficacy of these cells for the treatment of refractory lupus nephritis (LN) was verified. Specifically, 9 patients received systemic infusion of mesenchymal stem cells derived from adipose tissue and followed up for a 12-month follow-up period.Continue reading